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| | | Estimates of the acute toxicity of pesticides to birds. The approach followed is outlined in detail in Mineau et al. (2001). It consists of constructing a mathematical distribution of all available data for each pesticide. When data are insufficient to construct such a distribution, an extrapolation factor which is based on the known relative susceptibility of the test species is used instead. The listed reference values are calculated to be the best estimates of the LD50 for a bird species at the 5% tail of the distribution of sensitivity to a given pesticide regardless of its body size. |
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| | | Current AIHA Workplace Environmental Exposure Levels (WEEL) Guides (2007). Goal is to develop Workplace Environmental Exposure Level (WEEL) guides for chemical and physical agents and stresses |
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| | | Pesticide use on cotton reported to Arizona 1998 - 2000 |
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| | | ATSDR’s Division of Toxicology and Environmental Medicine publishes the Completed Exposure Pathway Site Count Report. A completed exposure pathway (CEP) is an exposure pathway that links a contaminant source to a receptor population. |
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| | | The Hazardous Substances Emergency Events Surveillance (HSEES) system was established by ATSDR to collect and analyze information about acute releases of hazardous substances and threatened releases that result in a public health action such as an evacuation. 14 state health departments currently participate. |
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| | | ATSDR Interaction Profiles for Toxic Substances; mixtures found at NPL sites |
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| | | ATSDR Medical Management Guidelines (MMGs) |
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| | | ATSDR MRL (Minimal Risk Levels (MRLs) for Hazardous Substances) |
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| | | The priority data needs (PDN) represent essential information to improve the database for conducting public health assessments. |
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| | | Status of ATSDR Priority Data Needs (PDN). The priority data needs represent essential information to improve the database for conducting public health assessments. |
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| | | The ATSDR Public Health Statements (PHSs) are a series of summaries about hazardous substances developed by the ATSDR Division of Toxicology. |
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| | | ATSDR ToxFAQ: This source provides summaries about hazardous substances developed by the CDC ATSDR (Agency for Toxic Substances and Disease Registry) Division of Toxicology, especially concerning exposure to hazardous substances found around hazardous waste sites and the effects of exposure on human health. |
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| | | The ATSDR ToxGuides (TM) are quick reference guides excerpted from the corresponding toxicological profiles. |
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| | | Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. |
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| | | Health and environmental health profiles prepared for 93 priority substances by Australian NPI (National Pollutant Inventory). |
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| | | Australian NPI (National Pollutant Inventory) emission reporting thresholds for 93 priority substances. |
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| | | California Department of Pesticide Regulations 2006 List of Residues in Fresh Produce |
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| | | California Department of Pesticide Regulations 1998 Report on Pesticide Use (1991 - 1998) |
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| | | California EPA list of substances of concern for cancer and developmental defects |
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| | | California Environmental Monitoring Branch report on pyrethrin and phyrethroid fate characteristics |
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| | | The California Office of Environmental Health Hazard Assessment (OEHHA) Toxicity Critera Database |
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| | | California OEHHA Toxic Air Contaminants |
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| | | Public Health Goals. PHGs are concentrations of chemicals in drinking water that are not anticipated to produce adverse health effects following long-term exposures. OEHHA is required to consider potential adverse effects on members of subgroups that comprise a meaningful proportion of the population, including but not limited to infants, children, pregnant women, the elderly, and individuals with a history of serious illness. The public health goals are non-regulatory in nature but are to be used as the health basis to update the state's primary drinking water standards (maximum contaminant levels, or MCLs) established by the California Department of Public Health (DPH) for chemicals subject to regulation. |
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| | | California Air Resources Board (CARB) Annual Air Toxics summary - Statewide. |
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| | | California Air Resources Board (CARB) Children's School Bus Exposure Study |
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| | | CERCLA Priority List of Hazardous Substances this is a list published by ATSDR (Agency for Toxic Substances and Disease Registry) which is part of the Center for Disease Control. Each of the 275 chemical is provided with a toxicity score and a rank. |
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| | | NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) provides summaries of studies to determine human reproductive health risks of chemicals. |
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| | | Carcinogenic Potency Database (CPDB) is a resource of the results of 6540 chronic, long-term animal cancer tests on 1547 chemicals. From University of California at Berkeley. |
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| | | Indiana University School of Medicine Drug Interaction Table |
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| | | NCI Cancer Therapy Evaluation Program Cytochrome P450 Drug Interaction Tables. Only major substrates and effective inducers are listed. |
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| | | Danish EPA List - SMILES/CAS List downloaded from OECD QSAR Toolbox |
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| | | Danish EPA Report. Coformulants are widely used in the formulation of pesticides. The effects of eighteen pesticide coformulants were assessed for adverse health effects on the basis of available literature. |
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| | | U.S. Drug Enforcement Agency (DEA) Drugs and Chemicals of Concern |
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| | | DEA National Forensic Laboratory Information System (NFLIS) 2007 Report for 25 Most Frequently Identified Drugs |
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| | | U.S. Drug Enforcement Agency (DEA) Controlled Substance List, Schedule I |
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| | | U.S. Drug Enforcement Agency (DEA) Controlled Substance List, Schedule II |
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| | | U.S. Drug Enforcement Agency (DEA) Controlled Substance List, Schedule III |
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| | | U.S. Drug Enforcement Agency (DEA) Controlled Substance List, Schedule IV |
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| | | U.S. Drug Enforcement Agency (DEA) Controlled Substance List, Schedule V |
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| | | DOD Environmental Exposure Report of exposure to pesticides during the 1990-1991 Gulf War. Toxicity assessment was conducted to weigh available evidence regarding the potential for particular pesticide active ingredients to cause adverse health effects, and to provide an estimate of the relationship between exposure and the increased likelihood and severity of adverse health effects. |
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| | | U.S. Army Center for Health Promotion and Preventive Medicine Wildlife Toxicity Assessment (WTA) reports. |
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| | | U.S. Emissions of Halocarbons and Miscellaneous Greenhouse Gases, 1990-1998 |
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| | DOE GreenhouseGases Production |
| | US Estimated 1990 Production, Sales, and Emissions of CFCs and Other Greenhouse Gases |
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| | | Review of Indoor Air VOC Concentrations, Report to DOE |
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| | | Dow has committed to make publicly available safety assessments for its products globally. This product safety assessment is intended to give general information about the chemical (or categories of chemicals) addressed. |
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| | | The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. Reference: Wishart DS et al., DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2007 Dec 11 |
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| | | Distributed Structure-Searchable Toxicity |
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| | | EPA Fathead Minnow Acute Toxicity Data(DSSTox) |
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| | | Food and Drug Administration Maximum Recommended Daily Dose (DSSTox) |
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| | | GEO Chemical Structure Annotations |
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| | | High Production Volume Chemicals - Structure Index File (DSSTox) |
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| | | High Production Volume Chemicals Information System |
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| | | EPA Integrated Risk Information System (IRIS) http://www.epa.gov/iris/. A structure index file with links to webpage for each chemical (DSSTox) |
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| | | National Center for Toxicological Research Estrogen Receptor Data (DSSTox) |
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| | | National Toxicology Program Chemical Structure Index file. A structure index file with links to study page for each chemical for 5 Main Study Areas (DSSTox) |
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| | | National Toxicology Program High Throughput Screening Chemical Structure Index file chemicals being submitted for testing at the NIH NCGC Screening Center of the MLI, submitted to DPI and PubChem (DSSTox) |
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| | | EDGE2 (Environment, Drugs and Gene Expression) is a scientific resource for toxicology-related gene expression information. The site contains databases and analyses of gene expression studies following exposure to a variety of chemicals or physiological changes. The ultimate goal of the EDGE is to map transcriptional changes from chemical exposure that will someday be used as a diagnostic "fingerprint" to predict toxicity as well as provide valuable insights into the basic molecular changes responsible. |
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| | | EU EINECS chemical list - SMILES/CAS List downloaded from OECD QSAR Toolbox |
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| | Environment Canada DSL (2007) |
| | Environment Canada Domestic Substances List (2007) (Reproduced with the permission of the Minister of Public Works and Government Services Canada, 2008) |
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| | | AEGLs represent threshold exposure limits for the general public and are applicable to emergency exposure periods ranging from 10 min to 8 h. AEGL-2 and AEGL-3, and AEGL-1 values as appropriate, will be developed for each of five exposure periods (10 and 30 min, 1 h, 4 h, and 8 h) and will be distinguished by varying degrees of severity of toxic effects. It is believed that the recommended exposure levels are applicable to the general population including infants and children, and other individuals who may be susceptible. Final AEGLs will be published by the National Research Council, National Academy of Sciences (NRC/NAS) following NRC/NAS peer review. The NAS publications may differ slightly from the final AEGL technical support documents due to editorial changes. |
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| | | AEGLs represent threshold exposure limits for the general public and are applicable to emergency exposure periods ranging from 10 min to 8 h. AEGL-2 and AEGL-3, and AEGL-1 values as appropriate, will be developed for each of five exposure periods (10 and 30 min, 1 h, 4 h, and 8 h) and will be distinguished by varying degrees of severity of toxic effects. It is believed that the recommended exposure levels are applicable to the general population including infants and children, and other individuals who may be susceptible. Holding Status AEGLs have been reviewed by the NAC/AEGL Committee and are on hold due to insufficient data to develop AEGL values. |
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| | | AEGLs represent threshold exposure limits for the general public and are applicable to emergency exposure periods ranging from 10 min to 8 h. AEGL-2 and AEGL-3, and AEGL-1 values as appropriate, will be developed for each of five exposure periods (10 and 30 min, 1 h, 4 h, and 8 h) and will be distinguished by varying degrees of severity of toxic effects. It is believed that the recommended exposure levels are applicable to the general population including infants and children, and other individuals who may be susceptible. Interim AEGLs are established following review and consideration by the National Advisory Committee for AEGLs (NAC/AEGL) of public comments on Proposed AEGLs. Interim AEGLs are available for use by organizations while awaiting NRC/NAS peer review and publication of Final AEGLs. Changes to Interim values and Technical Support Documents may occur prior to publication of Final AEGL values. |
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| | | AEGLs represent threshold exposure limits for the general public and are applicable to emergency exposure periods ranging from 10 min to 8 h. AEGL-2 and AEGL-3, and AEGL-1 values as appropriate, will be developed for each of five exposure periods (10 and 30 min, 1 h, 4 h, and 8 h) and will be distinguished by varying degrees of severity of toxic effects. It is believed that the recommended exposure levels are applicable to the general population including infants and children, and other individuals who may be susceptible. Proposed AEGLs are published in the Federal Register for public comment following review and concurrence of Draft AEGLs by the NAC/AEGL. The comment period is 30 days from the date Proposed AEGLs are published in the Federal Register. |
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| | | AEGLs represent threshold exposure limits for the general public and are applicable to emergency exposure periods ranging from 10 min to 8 h. AEGL-2 and AEGL-3, and AEGL-1 values as appropriate, will be developed for each of five exposure periods (10 and 30 min, 1 h, 4 h, and 8 h) and will be distinguished by varying degrees of severity of toxic effects. It is believed that the recommended exposure levels are applicable to the general population including infants and children, and other individuals who may be susceptible. This list of 371 priority chemicals is a composite of numerous priority lists of acutely toxic chemicals and represents the selection of chemicals for AEGL development by the NAC/AEGL during the next several years. The list has been assembled from the individual lists of chemicals nominated by NAC/AEGL member organizations for AEGL development. The priority list of chemicals, published in notice, is subject to modification as priorities of the NAC/AEGL committee or the NAC/AEGL member organizations change, it is anticipated that most of the chemicals on the priority list will remain as higher priority for AEGL development during the next several years. |
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| | | The attached list provides an overview of chemicals evaluated for carcinogenic potential by the Health Effects Division (HED) of the Office of Pesticide Programs (OPP) through December 2005. Applying the Agency’s Guidelines for Carcinogen Risk Assessment, the classification of the chemical is made by HED’s Cancer Assessment Review Committee (CARC). In addition to the OPP classification, this list includes those chemicals evaluated by peer review committees in two other Agency workgroups (indicated in the table by their acronyms): the Carcinogen Assessment Group (CAG); and the Carcinogen Risk Assessment Verification Endeavor (CRAVE).This list includes the chemical name, CAS Number, PC code, the cancer classification, reviewing organization, date reviewed, species, tumor types. It should be noted that the evaluation of many of these chemicals is an ongoing process, therefore, the information in this list (i.e., classification and/or the quantification) may be subject to change as new and/or additional data are submitted to OPP. This list should not be used as the single source for either the classification or quantification of the carcinogenic potential. This list will be updated annually. |
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| | | EPA has drinking water regulations for more than 90 contaminants. The Safe Drinking Water Act (SDWA) includes a process that must be followed to identify and list unregulated contaminants which may require a national drinking water regulation in the future. EPA must periodically publish this list of contaminants (called the Contaminant Candidate List or CCL). On March 2, 1998, EPA announced the first Drinking Water Contaminant Candidate List (CCL 1) |
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| | | EPA has drinking water regulations for more than 90 contaminants. The Safe Drinking Water Act (SDWA) includes a process that must be followed to identify and list unregulated contaminants which may require a national drinking water regulation in the future. EPA must periodically publish this list of contaminants (called the Contaminant Candidate List or CCL). On February 23, 2005, EPA announced the second Drinking Water Contaminant Candidate List (CCL) |
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| | | EPA has drinking water regulations for more than 90 contaminants. The Safe Drinking Water Act (SDWA) includes a process that must be followed to identify and list unregulated contaminants which may require a national drinking water regulation in the future. EPA must periodically publish this list of contaminants (called the Contaminant Candidate List or CCL). In February 2008 EDA announced the draft CCL 3 |
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| | | Summary information from the EPA ECOTOX database |
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| | | EPA 2006 Edition of the Drinking Water Standards and Health Advisories |
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| | | Summary information from the EPA ECOTOX database |
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| | | EPA Endocrine Disruptor Screening Program. Listed is an alphabetized draft list of the 73 pesticide active ingredients and HPV/pesticide inert chemicals selected for Tier 1 screening. This draft list was published in a Federal Register Notice in June 2007. Because this list of chemicals was selected on the basis of exposure potential only, it should not be construed or characterized as a list of known or likely endocrine disruptors. |
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| | | EPA Pesticide Mode of Action Database. |
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| | | National inventory of air toxics emissions from sources in the contiguous 48 states, Puerto Rico and the Virgin Islands. |
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| | | EPA National Emission Inventory database provides estimates of annual emissions of criteria and hazardous air pollutants from all types of sources. |
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| | | EPA National Emission Inventory database provides estimates of annual emissions of criteria and hazardous air pollutants from all types of sources. |
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| | | Dose-response assessments that the Office of Air Quality Planning and Standards (OAQPS) uses for risk assessments of hazardous air pollutants; values for short-term (acute) inhalation exposures. The data is compiled assessments from various sources for many of the 188 substances listed as hazardous air pollutants ("air toxics") under the Clean Air Act Amendments of 1990. |
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| | | EPA Chemical Accidental Release Prevention (ARP). Threshold quantities are established for toxic substances ranging from 500 to 20,000 pounds. The goals of the chemical accident prevention provisions are to focus on chemicals that pose a significant hazard to the community should an accident occur, to prevent their accidental release and to minimize the consequences of such releases. |
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| | | Dose-response assessments that the Office of Air Quality Planning and Standards (OAQPS) uses for risk assessments of hazardous air pollutants; values for long-term (chronic) inhalation and oral exposures. The data is compiled assessments from various sources for many of the 188 substances listed as hazardous air pollutants ("air toxics") under the Clean Air Act Amendments of 1990. |
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| | | Health Effects Notebook for Hazardous Air Pollutants. The fact sheets available describe the effects on human health of substances that are defined as hazardous by the 1990 amendments of the Clean Air Act. These substances include certain volatile organic chemicals, pesticides, herbicides, and radionuclides. |
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| | | The U.S. high production volume (HPV) chemicals are those which are manufactured in or imported into the United States in amounts equal to or greater than one million pounds per year. This list is taken from the 2002 Inventory Update Rule (IUR) List |
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| | | Under the High Production Volume (HPV) Challenge Program, companies are "challenged" to make health and environmental effects data publicly available on chemicals produced or imported in the United States in the greatest quantities. HPV chemicals are classified as those chemicals produced or imported in the United States in quantities of 1 million pounds or more per year. As of June 2007, companies have sponsored more than 2,200 HPV chemicals, with approximately 1,400 chemicals sponsored directly through the HPV Challenge Program and over 860 chemicals sponsored indirectly through international efforts. Access to HPV chemical information enables the public to participate in environmental decision-making at all levels - federal, state, and local. With voluntary data collection nearing its conclusion, the focus of the HPV Challenge Program has shifted to data use, both by the public and by EPA in its mission to protect human health and the environment. |
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| | EPA HPV Challenge Structures |
| | EPA HPV chemical list - SMILES/CAS List downloaded from OECD QSAR Toolbox |
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| | | The High Production Volume Information System (HPVIS) is a database that provides access to health and environmental effects information obtained through the High Production Volume (HPV) Challenge. This program "challenges" companies to make this data publicly available on chemicals produced or imported into the United States in quantities of 1 million pounds or more per year. On this Web site, HPVIS enables users to search for summary information, test plans, and new data on HPV chemicals as they are received by the Agency. Currently, the HPVIS database contains over 340 submissions, representing almost 900 chemical substances, either as a single chemical submission or as a member of a chemical category. EPA is carefully reviewing HPV chemical data to characterize the hazards and risks associated with HPV chemicals. HPVIS contains HPV Chemical Hazard Characterizations prepared during EPA's ongoing review of the health and environmental effects data contained with each HPV Challenge Program submission. HPVIS also contains Risk-Based Prioritization documents prepared from EPA's examination of HPV Challenge hazard data along with chemical use and exposure information collected from the 2006 Inventory Update Reporting (IUR). These recommendation documents prioritize HPV chemicals for follow-up data collection or management actions based on their potential risks. |
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| | | A large collection of chemicals with structure that are contained in the HPVIS system - most are not HPV chemicals |
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| | | Minimal Risk FIFRA Section 25(b) Inert Ingredients are approved for use in minimal risk pesticide products under FIFRA Section 25(b); they are called 4A inert ingredients. The inert ingredients are also eligible for inclusion in FIFRA Section 25(b) pesticide products applied to food use sites (e.g., food crops, animals used for food, etc.). |
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| | | List 4A - Minimal Risk Inert Ingredients; permitted under National Organic Program (NOP) regulations; also used for purposes of FIFRA Section 25(b). |
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| | | List 4B - Other ingredients for which EPA has sufficient information to reasonable conclude that the current use pattern in pesticide products will not adversely affect the public health or the envorinment. Permitted under National Organic Program (NOP) regulations; also used for purposes of FIFRA Section 25(b). |
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| | EPA INERTS FMA Fragrances |
| | OPP Inert (other) Ingredients in Pesticide Products - FMA Fragrance Ingredient Database. The Fragrance Materials Association (FMA) developed, on its own initiative, a list of more than 1500 fragrance component ingredients. EPA is making this Fragrance Ingredient List (FIL) available to the public for use in the Pilot Notification Program. |
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| | | List 3 contained those chemicals considered to be inert ingredients of unknown toxicity. Upon review, some of the compounds in this list were re-classified. List 3 (2004) is not currently used by EPA for classifying inerts. |
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| | | EPA OPP Inert Ingredients of Toxicological Concern - Classified on the basis of peer-reviewed studies which demonstrated carcinogenicity, adverse reproductive effects, neurotoxicity or other chronic effects, developmental toxicity (birth defects), ecological effects or the potential for bioaccumulation. These inert ingredients are eligible for inclusion in FIFRA 25(b) pesticide products applied to non-food use sites only (e.g., ornamental plants, highway right-of-ways, rodent control, etc.) |
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| | | EPA OPP Inert Ingredients tolerance reassessment decision documents.A decision document includes the risk assessment and the decision memorandum. The Code of Federal Regulation describes how each inert ingredient may be used. |
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| | | IRIS (Integrated Risk Information System) is a compilation of electronic reports on specific substances found in the environment and their potential to cause human health effects. IRIS was initially developed for EPA staff in response to a growing demand for consistent information on substances for use in risk assessments, decision-making and regulatory activities. The information in IRIS is intended for those without extensive training in toxicology, but with some knowledge of health sciences. |
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| | | EPA developed a list of priority chemicals for 2008 from nominations from the EPA programs and from the public received in response to the December 22, 2006, Federal Register notice requesting public nominations (71 FR 77017). The list of chemicals which were nominated and which have been selected for inclusion in the 2008 IRIS agenda are presented. |
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| | | Assessments in Progress. The status and planned milestone dates for each assessment can be found on the IRIS Track system, accessible from the IRIS database. All health endpoints due to chronic exposure, cancer and noncancer, are being assessed unless otherwise noted. For all endpoints assessed, both qualitative and quantitative assessments are being developed where information is available. |
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| | | All IUR chemicals from 1986-2002 with non-confidential production volume. The file contains non-confidential information from reports filed under the Inventory Update Reporting (IUR) for the 1986, 1990, 1994, 1998, and 2002 reporting cycles. The file can be used to determine if a chemical was reported to the IUR and the range of its national aggregate production volume. The file contains chemical names and associated aggregate production volumes for all non-confidential chemicals reported under the IUR. |
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| | | 2002 TSCA IUR (Inventory Update Rule) List. This file contains information reported to EPA under the 2002 Inventory Update Rule (IUR). The deadline for companies to report was December 31, 2002. This database includes all information received by EPA that did not have problems associated with the submission, including requests from companies to update or correct their earlier filings. |
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| | EPA OPPIN AntiMicrobial Active |
| | Active antimicrobial ingredients, actively supported by EPA - downloaded from EPA OPPIN database August 2008 |
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| | | Pesticide active, antimicrobial or inert ingredients with food use tolerances or tolerance exemptions - downloaded from EPA OPPIN database August 2008 |
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| | | Pesticide Inert ingredients - list downloaded from EPA OPPIN database August 2008 |
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| | EPA OPPIN Pesticide Active |
| | Pesticide conventional active ingredients, actively supported by EPA - downloaded from EPA OPPIN database August 2008 |
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| | | Drinking Water Contaminants & their MCLs (Maximum Containment Level). National Primary Drinking Water Regulations (NPDWRs or primary standards). |
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| | | Unregulated Contaminant Monitoring Regulation (UCMR) for Public Water Systems (PWSs) supporting the UCM-State Rounds 1 and 2 (1988-1997) |
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| | | Unregulated Contaminant Monitoring Regulation (UCMR) for Public Water Systems (PWSs) |
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| | | National Recommended Water Quality Criteria (Nonpriority Pollutants). These criteria are published pursuant to Section 304(a) of the Clean Water Act (CWA) and provide guidance for states and tribes to use in adopting water quality standards. |
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| | | National Recommended Water Quality Criteria (Organoleptic Effects). These criteria are published pursuant to Section 304(a) of the Clean Water Act (CWA) and provide guidance for states and tribes to use in adopting water quality standards. |
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| | | National Recommended Water Quality Criteria (Priority Pollutants). These criteria are published pursuant to Section 304(a) of the Clean Water Act (CWA) and provide guidance for states and tribes to use in adopting water quality standards. |
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| | | EPA has drinking water regulations for more than 90 contaminants. The Safe Drinking Water Act (SDWA) includes a process that we must follow to identify and list unregulated contaminants which may require a national drinking water regulation in the future. EPA must periodically publish this list of contaminants (called the Contaminant Candidate List or CCL). The preliminary (PCCL) lists 560 from an initial list 7500 contaminants that should be further evaluated. |
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| | | EPA Pesticide Fate Database - all active ingredients, including those with fate studies. Over 480 compounds, with physical and chemical properties and/or degradates. |
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| | | EPA Pesticide Fate Database. The information contained in the Pesticide Fate Database may be used by environmental scientists and researchers to describe or predict what could happen to a pesticide active ingredient under various conditions when it is released into the environment. The data are derived from studies submitted by pesticide manufacturers (registrants) in support of the registration/reregistration of their pesticide products. The Pesticide Fate Database contains data on: physical and chemical properties; chemical fate; transport of pesticide active ingredients registered in the United States; degradates or breakdown products of these registered pesticides; endpoint information such as half-lives and soil-water partitioning coefficients; It may be used to: model or predict the fate of pesticides in the environment; develop exposure characterizations that describe the potential exposure of plants, animals, and water resources to pesticide residue |
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| | | Most Commonly Used Conventional Pesticide Active Ingredients; Agricultural Market Sector (estimated), Ranked by Range in Millions of Pounds of Active Ingredient. |
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| | | EPA Pesticide Fact Sheets: The EPA provides fact sheets on new pesticide active ingredients (registered since 1997) from two sites, based on whether the ingredient is intended to be used as a conventional pesticide (miticide, insecticide, fungicide, herbicide, rodenticide, plant growth regulator, ovicide, nematicide, insect repellant) or a biopesticide. The respective web sites are http://www.epa.gov/opprd001/factsheets/ and http://www.epa.gov/pesticides/biopesticides/ingredients/index.htm. A fact sheet with summary toxicology information is provided for each chemical. |
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| | | EPA Pesticide Fact Sheets: The EPA provides fact sheets on new pesticide active ingredients (registered since 1997) from two sites, based on whether the ingredient is intended to be used as a conventional pesticide (miticide, insecticide, fungicide, herbicide, rodenticide, plant growth regulator, ovicide, nematicide, insect repellant) or a biopesticide. The respective web sites are http://www.epa.gov/opprd001/factsheets/ and http://www.epa.gov/pesticides/biopesticides/ingredients/index.htm. A fact sheet with summary toxicology information is provided for each chemical. |
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| | | EPA OPP expedited review and regulatory decision-making process for conventional pesticides that pose less risk to human health and the environment than existing conventional alternatives. |
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| | | EPA Region 3 Risk-Based Concentrations. This is a collection of Reference Doses (RfDs) and cancer slope factors developed by Region 3 of the USEPA. The data is combined to with standard exposure scenarios to derive so-called risk based concentrations. |
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| | | EPA Office of Pesticide Programs: EPA is reviewing older pesticides (those initially registered prior to November 1984) under FIFRA to ensure that they meet current scientific and regulatory standards. The results of EPA's reviews are summarized in Reregistration Eligibility Decision (RED) documents. |
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| | | EPA Risk-Screening Environmental Indicators (RSEI). This is a computer-based screening tool developed by EPA that analyzes risk factors to put Toxics Release Inventory (TRI) release data into a chronic health context. RSEI provides a full risk-related perspective for air and water releases, and hazard-based and pounds-based perspectives releases to air, water, and land. The full risk-related perspective covers over 400 chemicals and chemical categories, and over 50,000 reporting facilities (over all 18 years). |
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| | | A set of structures generated for compounds in SRS, using a name-to-structure conversion |
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| | | The Consolidated List of Chemicals Subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and Section 112(r) of the Clean Air Act (also known as the List of Lists) was prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 313 of EPCRA and, for a specific chemical, what reports may need to be submitted. |
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| | | EPA Toxics Release Inventory List. The Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and other waste management activities reported annually by certain covered industry groups as well as federal facilities. This inventory was established under the Emergency Planning and Community Right-to-Know Act of 1986 (EPCRA) and expanded by the Pollution Prevention Act of 1990. |
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| | | List of Toxic Chemicals within the Glycol Ethers Category of the EPA Toxics Release Inventory (TRI) |
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| | | TRI PBT CHEMICAL LIST . Persistent, bioaccumulative, and toxic chemicals extracted from current list of TRI Chemicals |
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| | | Data for 1988; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1989; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1990; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1991; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1992; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1993; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1994; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1995; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1996; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1997; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1998; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 1999; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2000; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2001; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2002; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2003; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2004; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2005; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | Data for 2006; the Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by certain industries as well as federal facilities. |
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| | | The Master Testing List (MTL) presents a consolidated listing of OPPT's Existing Chemical Testing Program priorities as well as those brought forward to OPPT by other EPA Program Offices, other Federal agencies, the TSCA Interagency Testing Committee, and international organizations such as the Organization for Economic Cooperation and Development (OECD). |
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| | | EPA TSCA Chemical list - SMILES/CAS List downloaded from OECD QSAR Toolbox |
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| | | Sunset Dates/Status for Chemicals Subject to TSCA Section 4 Actions |
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| | | European chemical Substances Information System (ECB ESIS) IUCLID Chemical Data Sheets |
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| | | European chemical Substances Information System (ECB ESIS) HPV (High Production Volume Chemicals) The current list contains information on 2,782 substances extracted from the IUCLID (International Uniform Chemical Information Database), where data have been reported by industry. |
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| | | European chemical Substances Information System (ECB ESIS) LPV (Low Production Volume Chemicals). The current list contains information on 7.832 substances extracted from the IUCLID (International Uniform Chemical Information Database), where data have been reported by industry. |
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| | | European chemical Substances Information System (ESIS). The list of No-Longer Polymers (NLP) are chemicals that have been on the EU market between September 18, 1981, and October 31, 1993 and are no longer considered to be polymers. |
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| | | European chemical Substances Information System (ECB ESIS) ORATS (Online EUropean Risk Assessment Tracking System) |
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| | | European chemical Substances Information System (ECB ESIS) PBT (Persistent Bioaccumulating Toxins) |
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| | | The DID list contains a number of detergent ingredients and their environmental properties and some parameters based on environmental properties. It has been harmonized for Eco-labeling. |
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| | | European Database Export Import of Dangerous Chemicals. Part 1 lists the chemicals or chemical groups that are subject to export notification. The chemicals are listed in Annex I to the Regulation (Regulation (EC) No 304/2003 of the European Parliament) |
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| | | European Database Export Import of Dangerous Chemicals. Part 2 lists the chemicals that qualify for PIC (prior informed consent) notification because they are banned or severely restricted within the Community in a Convention use category (i.e. pesticide or industrial chemical). The chemicals are listed in Annex I to the Regulation (Regulation (EC) No 304/2003 of the European Parliament) |
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| | | European Database Export Import of Dangerous Chemicals. Part 3: List of chemicals subject to the PIC procedure under the Rotterdam Convention |
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| | | These lists are representative of the basic materials used in perfumes and aromatic compositions. The lists were compiled mainly on the basis of information provided by EFFA (European Flavour and Fragrance Association). They constitute the inventory of fragrance ingredients. |
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| | | CosIng is the European Commission database with information on cosmetic ingredients contained in the: - "Cosmetics Directive" 76/768/EEC (Cosmetics Directive) Annex IV is the list of colouring agents allowed for use in cosmetic products. |
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| | | CosIng is the European Commission database with information on cosmetic ingredients contained in the: - "Cosmetics Directive" 76/768/EEC (Cosmetics Directive). |
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| | | CosIng is the European Commission database with information on cosmetic ingredients contained in the: - "Cosmetics Directive" 76/768/EEC (Cosmetics Directive) Annex VII is the list of UV filters allowed for use in cosmetic products. |
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| | | Identification of potentially bioaccumulative and persistent chemicals using QSAR; prepared by Danish EPA. QSARs should be used for initial identification of potential vPvBs (Very Persitent and Very Bioaccumulative substances) and PBT (Persistent, Bioaccumulative and Toxic substances) under EU guidance. |
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| | | List of 44 cosmetic ingredients (hair dyes) positively assessed by the Scientific Committee on Consumer Products of the European Union. |
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| | | List of hair dyes provisionally allowed by the Eusopean Commission (EC); regulated by Council Directive 76/768/EEC |
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| | | Status of EU Community Strategy for Endocrine Disrupters; 2007 report |
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| | | Final Report - Study on Endocrine Disrupters in Drinking Water (results from 51 waterworks in 5 European countries). |
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| | EUROPA Endocrine Candidate |
| | The European Commission established a priority list of substances (553 compounds) for further evaluation of their role in endocrine disruption. |
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| | EUROPA Food Contact Additives |
| | Eurpoean Commission, Directorate D - Food Safety: production and distribution chain; consolidated list of all (plastics) additives of Sections A and B appearing in the EC Directives on plastics for food. Lists maximum migrations and limits in finished product; also notes for specific compounds. |
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| | EUROPA Food Contact Monomers |
| | Eurpoean Commission, Directorate D - Food Safety: production and distribution chain; consolidated list of all monomers of Sections A and B appearing in the EC Directives on plastics for food. Lists maximum migrations and limits in finished product; also notes for specific compounds. |
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| | EUROPA Food Contact Provisional |
| | This provisional list of additives for use in plastic food contact materials and articles contains those additives for which a valid petition has been received by 31 December 2006. The list is expected to become positive 1 January 2010. The substances on the list have not necessarily been evaluated by EFSA (European Food Safety Authority). |
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| | | Imports of animals and their products from third countries: Provision of guarantees equivalent to EU requirements on residues of veterinary medicines, pesticides and contaminants. Substances or groups of substances that should be monitored for each animal species or product (EC). |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 1996 in the 15 EU Member States and Norway. Includes a summary of pesticide residues in and on products of plant origin and estimates of actual dietary pesticide exposure throughout Europe. |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 1997 in the 15 EU Member States and Norway. Includes a summary of pesticide residues in and on products of plant origin and estimates of actual dietary pesticide exposure throughout Europe. |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 1998 in the 15 EU Member States and Norway. Includes a summary of pesticide residues in and on products of plant origin and estimates of actual dietary pesticide exposure throughout Europe. |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 1999 in the 15 EU Member States and Norway and Iceland. Includes a summary of pesticide pesticide residues in and on products of plant origin and estimates of actual dietary pesticide exposure throughout Europe. |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 2000 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement1 (Norway, Iceland and Liechtenstein). Includes a summary of pesticide pesticide residues in and on products of plant origin and estimates of actual dietary pesticide exposure throughout Europe. |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 2001 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement1 (Norway, Iceland and Liechtenstein). |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 2002 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement1 (Norway, Iceland and Liechtenstein). |
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| | | The report covers the national situations with regard to pesticide residues monitoring for the calendar year 2003 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement1 (Norway, Iceland and Liechtenstein). |
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| | | Estimation of the chronic risk and acute risk to the consumer for the commodities investigated in the EU coordinated programme; calculations based on consumption figures from the World Health Organisation (Standard European Diet). The 2003 report covers the national situations with regard to pesticide residues monitoring for the calendar year 2001 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement (Norway, Iceland and Liechtenstein). |
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| | | Estimation of the chronic risk and acute risk to the consumer for the commodities investigated in the EU coordinated programme; calculations based on consumption figures from the World Health Organisation (Standard European Diet). The 2003 report covers the national situations with regard to pesticide residues monitoring for the calendar year 2002 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement1 (Norway, Iceland and Liechtenstein). |
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| | | Estimation of the chronic risk and acute risk to the consumer for the commodities investigated in the EU coordinated programme; calculations based on consumption figures from the World Health Organisation (Standard European Diet). The 2003 report covers the national situations with regard to pesticide residues monitoring for the calendar year 2003 in the 15 EU Member States and the three EFTA States who have signed the EEA agreement1 (Norway, Iceland and Liechtenstein). |
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| | | As a first stage, vitamins and minerals used as ingredients of food supplements will be included in the rule-making process under Directive 2002/46/EC. |
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| | | EPARs for authorised medicinal products for veterinary use; The EMEA publishes information on the products assessed by the Committee for Medicinal Products for Veterinary Use (CVMP). More detailed information is published later, following the granting of a Marketing Auhtorisation by the European Commission as an European Public Assessment Report (EPAR). |
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| | | Environmental Working Group (EWG) Human Toxome Project which is testing the full scope of industrial pollution in humanity. |
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| | | EXTOXNET Pesticide Information Profiles: This is a DOWNLOAD of toxicology information on pesticides written by toxicologists at several US land grant universities with the goal of providing unbiased information on pesticide toxicity. |
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| | | FDA Cumulative Estimated Daily Intake/Acceptable Daily Intake Database |
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| | FDA ColorAdditives Exempt |
| | Color additives approved for use in food, drugs, cosmetics and medical devices. Exempt additives are exempt from batch registration. |
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| | FDA ColorAdditives Nonexempt |
| | Color additives approved for use in food, drugs, cosmetics and medical devices. Batch registration is required. |
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| | | FDA Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers. |
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| | | FDA Generally Regarded as Safe List / EAFUS: A Food Additive Database |
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| | | FDA Generally Regarded as safe |
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| | | FDA Drug Development and Drug Interactions: Major Human Transporters. |
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| | | FDA List of "Indirect" Additives Used in Food Contact Substances |
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| | | FDA Maximum Recommended Therapeutic Dose (MRTD) Database (non-proprietary data). From FDA Center for Drug Evaluation and Research. |
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| | | FDA CFSAN, Office of Plants and Dairy Foods and Beverages; information about pesticides of interest to the FDA because of their potential for use on foods. Data include names, molecular formulas,use and references to CFR sections that list food tolerances. |
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| | | A list of chemicals that are used as retardants - derived from INCHEM EHC 1997 |
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| | | GerES III was a cross sectional sample of 4822 adults aged 18 to 69 years 120 sampling locations (response rate: 54.5 %) representative of the German population with regard to community size, age and gender. Samples were taken of whole blood, morning urine, tap water (not included in ACToR) and the contents of vacuum cleaner bags. The fourth German Environmental Survey (GerES IV) was conducted between May 2003 - May 2006. It was the first environmental survey referring exclusively to the examination of children and their environmental exposure. The study included a representative cross-sectional random sample of children aged 3 to 14 years in Germany. The survey was based on the examination of both blood and urine specimens sampled from the children as well as house dust and drinking water samples (not included in the ACTor database) from the corresponding households. |
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| | | The fourth German Environmental Survey (GerES IV) was conducted between May 2003 - May 2006. It was the first environmental survey referring exclusively to the examination of children and their environmental exposure. The study included a representative cross-sectional random sample of children aged 3 to 14 years in Germany. The survey was based on the examination of both blood and urine specimens sampled from the children as well as house dust and drinking water samples (not included in the ACTor database) from the corresponding households. |
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| | | The GESTIS-Substance Database contains information for the safe handling of hazardous substances and other chemical substances at work, e.g. health effects, necessary protective measures and such in case of danger (incl. First Aid). Furthermore the user is offered information upon important physical and chemical properties for these substances as well as special statutory regulations and regulations of the Berufsgenossenschaften. The available information relates to about 8,000 substances. Data are updated immediately after publication of new official regulations or after the issue of new scientific results. |
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| | | The Great Lakes Regional Toxic Air Emissions Inventory was developed by the eight Great Lakes states and the Province of Ontario. The 1999 emissions inventory presents a multijurisdictional inventory of point and area sources of toxic air emissions that have the potential to impact environmental quality in the Great Lakes region. |
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| | | The Great Lakes Regional Toxic Air Emissions Inventory was developed by the eight Great Lakes states and the Province of Ontario. The 1999 emissions inventory presents a multijurisdictional inventory of point and area sources of toxic air emissions that have the potential to impact environmental quality in the Great Lakes region. |
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| | | The Great Lakes Regional Toxic Air Emissions Inventory was developed by the eight Great Lakes states and the Province of Ontario. The 2002 emissions inventory presents a multijurisdictional inventory of point, area and mobile sources of toxic air emissions that have the potential to impact environmental quality in the Great Lakes region. |
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